Evaluation of Buprenorphine Rotation in Patients Receiving Long-term Opioids for Chronic Pain- A Systematic Review
The risks of long-term opioid use are well-documented. However, whether switching from a full opioid agonist to the partial opioid agonist buprenorphine improves pain-related outcomes and maintains acceptable side effects in patients with chronic pain remains uncertain. This systematic review of 22 studies focusing on the outcomes of switching to buprenorphine indicates, with low-quality evidence, […]
Making Pain Research More Inclusive
Much of our knowledge about pain mechanisms and treatments is derived from studies involving participants who are generally healthier, wealthier, younger, and predominantly White. This lack of diversity restricts the relevance of these findings and impedes the creation of effective interventions for various populations. To ensure equitable benefits in pain research, it is essential to […]
The Efficacy of Graded Motor Imagery and Its Components on Phantom Limb Pain and Disability: A Systematic Review and Meta-Analysis
Phantom limb pain (PLP) is a common condition after amputation, affecting up to 87% of people. It causes pain and discomfort where the limb is missing. PLP can be hard to treat and can affect a person’s mental and physical well-being.
Cognition and Pain: A Review
Our brains play a crucial role not only in feeling pain but also in understanding and remembering it. This review explores the growing body of evidence suggesting that pain can negatively impact cognitive abilities like memory and focus. We’ll delve into the brain regions involved in both pain and cognition, as well as how certain pain medications might […]
2025 PainSA Research Grant: Call For Applications
PainSA offers two research grants annually to advance knowledge and research capabilities in the field of pain and pain management. Each year, two grants are awarded: Both grants require the research to focus on pain. The study program can be undertaken on either a part-time or full-time basis. Application is open from July 22nd – […]
Persistent Physical Symptoms: Definition, Genesis, and Management
Persistent physical symptoms, also known as persistent somatic symptoms, encompass distressing somatic complaints lasting several months or more, regardless of their cause. These symptoms, often resulting in significant disability, pose a major burden on patients, healthcare professionals, and society. They can arise from infections, injuries, medical conditions, stressful life events, or appear without a clear […]
Is Pain Ever Acceptable? A Qualitative Exploration Concerning Adult Perceptions of Chronic Pain
Chronic pain is an all-too-common experience, affecting a significant portion of the adult population. A systematic review by Fayaz et al. (2016) reveals that between 35% and 51% of adults in the UK suffer from chronic pain, a condition that transcends mere physical discomfort to deeply impact overall quality of life. From limiting daily activities […]
Understanding Pain: Unravelling the Physiology, Assessment, and Management of Pain through South African Stories
“Understanding Pain: Unravelling the physiology, assessment, and management of pain through South African stories” is an open access pain textbook edited by Romy Parker and Jocelyn Park-Ross. The book was funded by an IASP Developing Countries Education Grant and published in early August 2024 by the University of Cape Town Libraries. The book is freely […]
The Fit-for-Purpose Model: Conceptualizing and Managing Chronic Non-specific Low Back Pain as an Information Problem
Chronic nonspecific low back pain (LBP) is a complex and multifaceted condition, affecting millions worldwide. Understanding the intricate nature of this condition is essential for developing effective treatments. This article introduces a model designed to explain the development and persistence of chronic LBP, integrating factors across the biopsychosocial spectrum. The Fit-for-Purpose model suggests that individuals […]
New Insights about Chronic Pelvic Pain Syndrome (CPPS)
Chronic pelvic pain syndrome (CPPS) is a condition defined by persistent pelvic discomfort lasting longer than six months, significantly disrupting daily life. Unlike other pelvic pain conditions, CPPS is not linked to menstrual cycles,pregnancy, injuries, or surgical interventions. This integrative article provides a multidisciplinary perspective on the experience of women with CPPS.