PainSA is a chapter of the International Association for the Study of Pain. Our mission is to improve all aspects of pain management in Southern Africa.

Efficacy of ketamine in relieving neuropathic pain

Neuropathic pain is a complex and often debilitating condition that affects millions of people worldwide. While there are various treatments available, such as opioids, anticonvulsants, and antidepressants, these treatments often fall short in providing long-lasting relief for patients. Nonetheless, recent research indicates that ketamine, an anesthetic drug, may offer a viable solution for treating neuropathic pain.
To improve our understanding of ketamine behavior under various administration conditions, we performed a systematic review and meta-analyses of controlled studies on the efficacy of ketamine in mice and rats with a disease model of nerve injury on relief of allodynia.